1. 水生态毒性和风险评价
2. 环境污染物的复合生物效应
3. 盐度对污染物生物效应的调控作用
1. 水生态毒性和风险评价
2. 环境污染物的复合生物效应
3. 盐度对污染物生物效应的调控作用
1.国家自然科学基金面上项目，盐度与吡虫啉复合胁迫下沙蚕的盐度适应性和毒性响应及机制，2025/01~2028/12，主持。
2.国家自然科学基金青年项目，环境浓度抗生素和纳米抗菌剂对生物膜和细菌抗药性的联合作用与机制，2019/01~2021/12，主持。
3.广东省青年提升项目，微塑料和环境浓度抗生素联合暴露对生物膜定殖及耐药性的影响和机制，2023/01~2025/12，主持。
4.广东省面上项目，微塑料和抗生素复合暴露对沙蚕及肠道微生物代谢和耐药性的影响，2024/01~2026/12，主持。
5.广东省面上项目，群体感应抑制剂对细菌抗性突变的阻遏效应和机制研究，2019/10-2022/9，主持。
6.国家自然科学基金-广东省联合基金，大湾区水体新卤代有机污染物的时空分布、多介质过程及生态风险评价，2024/01~2027-12-31，参与。
7.国家自然科学基金重点项目，微纳塑料与典型有机物的复合污染特征及对小动物的生物效应，2020/1-2024/12，参与。
8.国家自然科学基金-广东省联合基金，大湾区河口典型有机污染特征及基于多证据链的生态效应，2020/1~2023/12，参与。
（一）论文
1.Wang, D.; Ding, Q.; Zhong, Y.; Han, X.; Fu, L.; Yu, J.; Li, K.; You, J.* Effects of Erythromycin on Nereis Succinea and the Intestinal Microbiome across Different Salinity Levels. Environmental Science & Technology 2024, 58 (6), 2662–2671. https://doi.org/10.1021/acs.est.3c06984.
2.Wang, D.; Ren, J.; Tan, Z.; You, J.* Gut Microbial Profiles in Nereis Succinea and Their Contribution to the Degradation of Organic Pollutants. Environmental Science & Technology 2020, 54 (10), 6235–6243. https://doi.org/10.1021/acs.est.9b07854.
3.Han, X.; Fu, L.; Yu, J.; Li, K.; Deng, Z.; Shu, R.; Wang, D.*; You, J.; Zeng, E. Y. Effects of Erythromycin on Biofilm Formation and Resistance Mutation of Escherichia Coli on Pristine and UV-Aged Polystyrene Microplastics. Water Res. 2024, 256, 121628. https://doi.org/10.1016/j.watres.2024.121628.
4.Zhong, Y.; Ding, Q.; Huang, Z.; Xiao, X.; Han, X.; Su, Y.; Wang, D.*; You, J. Influence of Ultraviolet-Aging and Adsorbed Pollutants on Toxicological Effects of Polyvinyl Chloride Microplastics to Zebrafish. Environmental Pollution 2023, 316, 120617. https://doi.org/10.1016/j.envpol.2022.120617.
5.Wei, F.; Wang, D.*; Li, H.; You, J. Joint Toxicity of Imidacloprid and Azoxystrobin to Chironomus Dilutus at Organism, Cell, and Gene Levels. Aquatic Toxicology 2021, 233, 105783. https://doi.org/10.1016/j.aquatox.2021.105783.
6.Wang, D.; Zhong, Y.; Ding, Q.; Han, X.; Chen, K.; Pan, B.; You, J.* Distinct Effects of Nano-Polystyrene, Erythromycin and Their Mixtures on Composition and Metabolic Profile of Intestinal Microbiota in Nereis Succinea. Environ. Sci.: Nano 2023, 10, 2053-2065. https://doi.org/10.1039/D3EN00288H.
7.Su, Y.; Li, F.; Xiao, X.; Li, H.; Wang, D.*; You, J. Ecological Risk of Galaxolide and Its Transformation Product Galaxolidone: Evidence from the Literature and a Case Study in Guangzhou Waterways. Environ. Sci.: Processes Impacts 2023, 25, 1337-1346 https://doi.org/10.1039/D3EM00139C.
8.Xiao, X.; Tong, Y.; Wang, D.*; Gong, Y.; Zhou, Z.; Liu, Y.; Huang, H.; Zhang, B.; Li, H.; You, J. Spatial Distribution of Benthic Toxicity and Sediment-Bound Metals and Arsenic in Guangzhou Urban Waterways: Influence of Land Use. Journal of Hazardous Materials 2022, 439, 129634. https://doi.org/10.1016/j.jhazmat.2022.129634.
9.Wang, D.; Ning, Q.; Deng, Z.; Zhang, M.; You, J.* Role of Environmental Stresses in Elevating Resistance Mutations in Bacteria: Phenomena and Mechanisms. Environmental Pollution 2022, 307, 119603. https://doi.org/10.1016/j.envpol.2022.119603.
10.Ning, Q.; Wang, D.*; You, J. Joint Effects of Antibiotics and Quorum Sensing Inhibitors on Resistance Development in Bacteria. Environ. Sci.: Processes Impacts 2021, 23 (7), 995–1005. https://doi.org/10.1039/d1em00047k.
11.Ding, Q.; Yu, J.; Wang, D.*; You, J. Mutual Effects of Microplastics and Microbes: Tiny Things Have Big Impacts. Future Microbiology 2023, 18 (3), 159–162. https://doi.org/10.2217/fmb-2022-0237.
12.Wang, D.; Ning, Q.; Dong, J.; Brooks, B. W.; You, J.* Predicting Mixture Toxicity and Antibiotic Resistance of Fluoroquinolones and Their Photodegradation Products in Escherichia Coli. Environmental Pollution 2020, 262, 114275. https://doi.org/10.1016/j.envpol.2020.114275.
13.Ning, Q.; Wang, D.*; Cheng, F.; Zhong, Y.; Ding, Q.; You, J. Predicting Rifampicin Resistance Mutations in Bacterial RNA Polymerase Subunit Beta Based on Majority Consensus. BMC Bioinformatics 2021, 22 (1), 210. https://doi.org/10.1186/s12859-021-04137-0.
（二）论著
1. 江桂斌, 郑明辉, 冯玉杰, 王亚韡. 环境化学前沿(第三辑). 北京: 科学出版社, 2022 (参编)。
2. 曾永平. 全球环境问题概论. 北京: 科学出版社, 2019 (参编)。
（三）专利
1. 王大力；宁清；吴凡；游静；基于朴素贝叶斯模型的大肠杆菌利福平抗性突变预测方法，2020-12-9，中国，CN202011427488.8。
本科生课程：《环境管理与规划》《环境问题》
研究生课程：《生态风险评价》
本人所在暨南大学水生态风险评价与管理团队，现有“生物有效性与生物效应”、“复合污染风险识别与评价”、“环境污染与生物抗性”、“生物动力学与生态风险预测模型”、“生命周期分析与可持续发展”五个研究方向。团队以环境化学、生态毒理学及生物学为理论基础，致力于研究区域环境暴露与水生态风险，通过评估复合污染生态风险，从分子、细胞、个体到种群层面阐释污染物致毒机制，研发污染物识别评价新技术，探索新兴产业可持续性等多维度，以期在基础理论、方法技术创新等方面取得进步。
